Happy Sunday! We’ve been having a lovely weekend with my Pete's youngest son and luckily for us the sun has come out to play too! We did a spot of retail therapy yesterday followed by sunbathing in the back garden. Bliss. The evening followed with good food and a movie then off to bed for a very hot night. It’s unusual to have such humid weather here in the UK (I’m not complaining). I slept like a log although a bit disturbed right through till 8am again this morning. I’m sure I wouldn’t wake till ten am if Pete didn’t get up!
There have been lots of Google alerts on some research found for triple negative over the last few days. It seems there is an enzyme called CD73 which makes breast cancer more resistant to anthracycline chemotherapy, a treatment that works by killing tumour cells and activating the body’s anti-tumour immune response.
More importantly, the study revealed that over expression of CD73 stops the body’s immune system from responding to cancer. Additionally, elevated levels of CD73 bring about a higher risk of distant metastases, the principal cause of death in patients with breast cancer.
By examining its effect on laboratory animals, Dr. Stagg’s team discovered that the combination of anthracycline and anti-CD73 therapies prolonged survival by over 50 per cent. However researchers have to investigate further to see whether or not anti-CD73 treatments are effective with other chemotherapy treatments. Human trials of CD73 inhibitors may begin within as little as five years, bringing hope to the thousands of women and men battling breast cancer presently and in the future.
This research was jointly led by Professor Mark Smyth of The Queensland Institute of Medical Research, Australia, and was funded by the Canadian Institutes of Health Research, the Cancer Research Society, the National Health and Medical Research Council (NH&MRC) of Australia and the Susan G. Komen Foundation, USA.
This is exciting news as it seems this keeps coming up in the news.
Also a lady who has been reading my blogs has contacted me regarding dendritic cell therapy and some info she has found online from an Australian company.
"In order to make a dendritic cell therapy vaccine, tumour associated antigen needs to be obtained. This can be either from a biopsy of the tumour or part of a specimen removed at operation. Or, it can be obtained from the urine during any treatment programme, which destroys tumour cells, such as chemotherapy, or in our case at our clinic, we use high dose intravenous vitamin C and Ukrain (Chelidonium Majus and
In conventional chemotherapy maximal tumour cell death occurs from one day to six days after a chemotherapeutic dose. It is during the first two days of this that the patient is instructed to save their urine and by a special filtration process saving molecules of a particular molecular weight, we are able to isolate tumour antigen specific to that particular patient and use this in order to make a dendritic cell therapy vaccine."
"Therefore I would advise any patient following a conventional treatment programme, to save the urine and deep freeze it during the time of maximal tumour cell destruction and to look into having a dendritic cell therapy vaccine made, as this lessens the chance by
approximately 50%, of tumour recurrence. Just stimulating the immune system is too crude, in dendritic vaccines you stimulate the immune system to recognise specific tumour associated antigens, that is the key. General immuno-activation may not work. It has to be specific against that particular tumour, in that particular patient."
I will ask Dr Nesselhut what his thoughts on this are in due course. I am sure Dr Nesselhut knows what he is doing but it’s always worth asking.
How do I feel today? Good... I have been considering my daily routine with the diet and exercise and everything else and wonder if it’s something I can continue forever? I think the motivation for it is there but keeping it up is another thing. I like change and the feeling of growing and improving myself and wonder if doing this is enough?
Am I missing anything or is my body getting used to it and therefore not responding as well?
I have adapted my morning juice as mentioned before to get the best of both worlds of juicing and smoothing. I am going to call my Smoouice! Ha ha! I can’t stomach having powders in my juice so I have been juicing cucumber, ginger and celery then adding that juice to the blender with spinach and avocado with flaxseed and my other powders. It looks good and taste pretty good too. I think this is a good compromise and since I have been doing it I haven’t had an upset stomach. Phew.
Sometimes I think I just want a break from it all. But I can’t stop now. I still have fleeting thoughts of what’s round the corner and keep reading that stage 4 triple negative survivors are living longer but not going into remission. Maybe there are some out there but I am guessing they don’t bother going online telling people about it once they have become well. I don’t blame them. Living and breathing canSer is consuming. I’m lucky as I don’t feel ill and I don’t worry like I used to but I cannot believe it has almost been a year since the day they told me it is ‘incurable’. Pah. I still think it. How can they know with all the treatment that I am having that I will not be cured one day? But that’s the thing with canSer. Are you ever cured?
I have just read on my visitor’s page a lady who has got secondary canSer ten years after having breast canSer. That sucks... but I guess it’s a constant reminder that you never know what’s round the corner. All I know is that I don’t want this illness any more. I don’t want to live on red alert and always wondering if I am going to be well in six months time.
I suppose I am in control of all of that. CanSer doesn’t own me I own it and as far as I am concerned it has lost the battle and I fight to live another day better than the last. So there!